Discovery of new RNA molecule could be key for early detection of skin cancer

The discovery of a new RNA molecule could lead to earlier detection of squamous cell carcinoma in the future, according to a new study. The study, published in the American Journal of Pathology (Feb. 2020; 190(2):503-517), found that the molecule, named PRECSIT, is integral in determining how squamous cell carcinoma grows and spreads.

Repurposed topical cream may be key to curbing mosquito-borne diseases

Applied within an hour of mosquito bite, the topical cream imiquimod may reduce the chance of transmission of viral diseases such as Zika and dengue, according to a new study. Researchers of the study, published in Science Translational Medicine (Jan 22, 2020; 12(527)), found that the skin cream, when applied immediately after a mosquito bite, helps to activate immune system response.

Active ingredients in sunscreens may absorbed into skin at higher levels than previously thought

Absorption of the active ingredients in four commercially available sunscreens resulted in plasma concentrations that exceed the FDA safety threshold in participants in a new study. Researchers of the study, published in JAMA (Jan 21, 2020; 323(3):256-267) stressed that these findings do not suggest that individuals should stop using sunscreen.

Combination of Two Immunotherapies Brings Advanced Melanoma Survival Rate to 50% for First Time

By combining two existing therapies, researchers at the Royal Marsden NHS Foundation Trust in London have found that they have been able to stop or even reverse the progression of advanced melanoma in half of patients. The two therapies, ipilmumab and nivolumab, were tested on patients over the course of five years. The findings were published online ahead of print in the New England Journal of Medicine (Sept. 28, 2019).

New Model Helps Understand How Electricity Promotes Healing of Wounds

Researchers have discovered just how electrical stimulation helps to promote wound healing. Stimulating cells with electrical charges causes the cells to move toward the center of the wound, according to researchers of a new study. They discovered this with the help of a new tool that predicts how cells migrate within a wound, according to the study, which was published in the Journal of Theoretical Biology (June 15, 2019; 478:58-73).